Florian Marx, PhD

Research Fellow

Research theme: Combatting Infections of National Priority

Dr. Florian Marx is a Senior Researcher at SACEMA and the Desmond Tutu TB Centre (DTTC), Faculty of Medicine and Health Sciences of Stellenbosch University. He coordinates a joint SACEMA-DTTC Tuberculosis Modelling Partnership and Research Programme and leads the Working Group Data Analysis and Modelling (WGDAM). Before joining SACEMA, he received a PhD degree at Stellenbosch University (2018) and completed a research fellowship at Harvard Medical School (2014) and Yale School of Public Health (2015-16). He received a Masters Degree in Epidemiology from the London School of Hygiene and Tropical Medicine (2009) and a Medical Degree from Charite Berlin (2007). His research focusses on the epidemiology of tuberculosis and the public health impact of TB control interventions with a particular focus on high-incidence settings.

Recent publications

Pontali E, Silva DR, Marx, FM, Caminero JA, Centis R, Muhwa JC, Tiberi S, Migliori GB, (2022) Breathing back better! A state of the art on the benefits of functional evaluation and rehabilitation of post-tuberculosis and post-COVID lungs doi.org/10.1016/j.arbres.2022.05.010 Archivos de Bronconeumología

Moore DP, Hesseling AC, Marx FM (2022) Prolonged-course tuberculosis treatment or secondary prevention for those at high risk of recurrence? Clinical Microbiology and Infection doi.org/10.1016/j.cmi.2022.01.013

Marx FM; Meehan S-A; Jivan D; Dunbar R; Hoddinott G; Hesseling AC; Osman M; (2022) Use of interactive messaging to reduce pre-diagnosis loss to follow-up for TB care The International Journal of Tuberculosis and Lung Disease doi.org/10.5588/ijtld.21.0332

de Villiers AK; Dye D; Yaesoubi R; Cohen T; Marx FM (2022) Spatially targeted digital chest radiography to reduce tuberculosis in high-burden settings: A study of adaptive decision making Epidemics doi.org/10.1016/j.epidem.2022.100540

Marx FM, Hauer B, Menzies NA, Haas W, Perumal N (2021) Targeting screening and treatment for latent tuberculosis infection towards asylum seekers from high-incidence countries – a model-based cost-effectiveness analysis BMC Public Health doi.org/10.1186/s12889-021-12142-4

Migliori GB, Marx FM, Ambrosino N, Zampogna E, Schaaf HS, van der Zalm MM, Allwood B, Byrne AL, Mortimer K, Wallis RS, Fox GJ, Leung CC, Chakaya JM, Seaworth B, Rachow A, Marais BJ, Furin J, Akkerman OW, Al Yaquobi F, Amaral AFS, Borisov S, Caminero JA, Carvalho ACC, Chesov, D, Codecasa LR, Teixeira RC, Dalcolmo MP, Datta S, Dinh-Xuan AT, Duarte R, Evans CA, García-García JM, Günther G, Hoddinott G, Huddart S, Ivanova O, Laniado-Laborín R, Manga S, Manika K, Mariandyshev A, Mello FCQ, Mpagama SG, Muñoz-Torrico M, Nahid P, Ong CWM, Palmero DJ, Piubello A, Pontali E, Silva DR, Singla R, Spanevello A, Tiberi S, Udwadia ZF, Vitacca M, Centis R, D´Ambrosio L, Sotgiu G, Lange C, Visca, D. (2021) Clinical standards for the assessment, management and rehabilitation of post-TB lung disease International Union against Tuberculosis and Lung Disease doi.org/10.5588/ijtld.21.0425

Vanden Driessche K, Mahlobo PZ, Venter R, Caldwell J, Jennings K, Diacon AH, Cotton MF, de Groot R, Hens N, Marx FM, Warren RM, Mishra H, Theron G (2021) Face masks in the post-COVID-19 era: a silver lining for the damaged tuberculosis public health response? Lancet Respiratory Medicine doi: 10.1016/S2213-2600(21)00020-5

Marx, F.M, T. Cohen, N.A. Menzies, J.A. Salomon, & G. Theron (2020) Cost-effectiveness of post-treatment follow-up examinations and secondary prevention of tuberculosis in a high-incidence setting: a model-based analysis. The Lancet Global Health 8(9), e1223-e1233 doi: 10.1016/S2214-109X(20)30227-8

Allwood B.W, M. M. van der Zalm, A. F. S. Amaral, A. Byrne, S. Datta, U. Egere, C. A. Evans, D. Evans, D. M Gray, G. Hoddinott, O. Ivanova, R. Jones, G. Makanda, F. M. Marx, J. Meghji, S. Mpagama, J. G. Pasipanodya, A. Rachow, I. Schoeman, J. Shaw, C. Stek, S. van Kampen, D. von Delft, N. F. Walker, R. S. Wallis, & K. Mortimer (2020) Post-tuberculosis lung health: perspectives from the First International Symposium. The International Journal of Tuberculosis and Lung Disease 24(8):820–828 doi: 10.5588/ijtld.20.0067

Graham, R. N., L. Qian, K. Bruxvoort, F. M. Marx, L. K. Whittles, and J. Lewnard (2020) Inference of naturally-acquired immunity using a self-matched negative control design. Epidemiology doi: 10.1097/EDE.0000000000001305

Mishra.H., B. W. P. Reeve, Z. Palmer, J. Caldwell, T. Dolby, C. C. Naidoo, J. G. Jackson, S.G Schumacher, C. M. Denkinger, A. H. Diacon, P. D. van Helden, F. M. Marx, R. M.Warren, & G. Theron (2020) Xpert MTB/RIF Ultra and Xpert MTB/RIF for diagnosis of tuberculosis in an HIV-endemic setting with a high burden of previous tuberculosis: a two-cohort diagnostic accuracy study. The Lancet Respiratory Medicine 8(4): 368-382 doi: 10.1016/ S2213-2600(19)30370-4

Quaife, M., R. M. J. Houben, B. Allwood, T. Cohen, A.K Coussens, A.D. Harries, F.M. Marx, S. Sweeney, R.S. Wallis, & N. A. Menzies (2020) Post-tuberculosis mortality and morbidity: valuing the hidden epidemic. The Lancet Respiratory Medicine doi: 10.1016/S2213-2600(20)30039-4

Marx, F.M., T.Cohen, C. Lombard, A.C. Hesseling, S.S. Dlamini, N. Beyers, & P. Naidoo (2019) Notification of relapse and other previously treated tuberculosis in the 52 health districts of South Africa. The International Journal of Tuberculosis and Lung Disease 23,(8):891-899. Doi: 10.5588/ijtld.18.0609

Dippenaar, A., M. De Vos, F.M. Marx, S.A. Adroub, P.D. van Helden, A. Pain, S.L. Sampson, & R.M. Warren. (2019) Whole genome sequencing provides additional insights into recurrent tuberculosis classified as endogenous reactivation by IS6110 DNA fingerprinting. Infection, Genetics and Evolution 103948. doi: 10.1016/j.meegid.2019.103948

Osman, M., A. Welte, R. Dunbar, R. Brown, G. Hoddinott , A.C. Hesseling, & F.M Marx (2019) Morbidity and mortality up to 5 years post tuberculosis treatment in South Africa: A pilot study. International Journal of Infectious Diseases 85:57-63 doi: org/10.1016/j.ijid.2019.05.024

Marx F. M, Dunbar R, Enarson D. A, Williams B. G, Warren R. M, van der Spuy G. D, van Helden P. D, Beyers N. (2014) The temporal dynamics of relapse and reinfection tuberculosis after successful treatment: a retrospective cohort study. Clinical Infectious Diseases 58(12): doi: 10.1093/cid/ciu186.

DSI-NRF Centre of Excellence in Epidemiological Modelling and Analysis