Florian Marx, PhD

Senior Researcher

Research theme: Combatting Infections of National Priority

Dr. Florian Marx is a Senior Researcher at SACEMA and the Desmond Tutu TB Centre (DTTC), Faculty of Medicine and Health Sciences of Stellenbosch University. He coordinates a joint SACEMA-DTTC Tuberculosis Modelling Partnership and Research Programme and leads the Working Group Data Analysis and Modelling (WGDAM). Before joining SACEMA, he received a PhD degree at Stellenbosch University (2018) and completed a research fellowship at Harvard Medical School (2014) and Yale School of Public Health (2015-16). He received a Masters Degree in Epidemiology from the London School of Hygiene and Tropical Medicine (2009) and a Medical Degree from Charite Berlin (2007). His research focusses on the epidemiology of tuberculosis and the public health impact of TB control interventions with a particular focus on high-incidence settings.

Recent publications

Driessche, K.V., P.Z. Mahlobo, R. Venter, J. Caldwell, K. Jennings, A.H. Diacon, M.F. Cotton, R. de Groot, N. Hens, F.M. Marx, R.M. Warren, H. Mishra, & G. Theron (2021) Face masks in the post-COVID-19 era: a silver lining for the damaged tuberculosis public health response? The Lancet Respiratory Medicine doi: 10.1016/ S2213-2600(21)00020-5

Marx, F.M, T. Cohen, N.A. Menzies, J.A. Salomon, & G. Theron (2020) Cost-effectiveness of post-treatment follow-up examinations and secondary prevention of tuberculosis in a high-incidence setting: a model-based analysis. THE LANCET Global Health 8(9), e1223-e1233 doi: 10.1016/S2214-109X(20)30227-8

Allwood B.W, M. M. van der Zalm, A. F. S. Amaral, A. Byrne, S. Datta, U. Egere, C. A. Evans, D. Evans, D. M Gray, G. Hoddinott, O. Ivanova, R. Jones, G. Makanda, F. M. Marx, J. Meghji, S. Mpagama, J. G. Pasipanodya, A. Rachow, I. Schoeman, J. Shaw, C. Stek, S. van Kampen, D. von Delft, N. F. Walker, R. S. Wallis, & K. Mortimer (2020) Post-tuberculosis lung health: perspectives from the First International Symposium. The International Journal of Tuberculosis and Lung Disease 24(8):820–828 doi: 10.5588/ijtld.20.0067

Graham, R. N., L. Qian, K. Bruxvoort, F. M. Marx, L. K. Whittles, J. Lewnard (2020) Inference of naturally-acquired immunity using a self-matched negative control design. medRxiv doi: 10.1101/2020.03.01.20029850

Mishra.H., B. W. P. Reeve, Z. Palmer, J. Caldwell, T. Dolby, C. C. Naidoo, J. G. Jackson, S.G Schumacher, C. M. Denkinger, A. H. Diacon, P. D. van Helden, F. M. Marx, R. M.Warren, & G. Theron (2020) Xpert MTB/RIF Ultra and Xpert MTB/RIF for diagnosis of tuberculosis in an HIV-endemic setting with a high burden of previous tuberculosis: a two-cohort diagnostic accuracy study. The Lancet Respiratory Medicine 8(4): 368-382 doi: 10.1016/ S2213-2600(19)30370-4

Quaife, M., R. M. J. Houben, B. Allwood, T. Cohen, A.K Coussens, A.D. Harries, F.M. Marx, S. Sweeney, R.S. Wallis, & N. A. Menzies (2020) Post-tuberculosis mortality and morbidity: valuing the hidden epidemic. THE LANCET Respiratory Medicine doi: 10.1016/S2213-2600(20)30039-4

Marx, F.M., T.Cohen, C. Lombard, A.C. Hesseling, S.S. Dlamini, N. Beyers, & P. Naidoo (2019) Notification of relapse and other previously treated tuberculosis in the 52 health districts of South Africa. The International Journal of Tuberculosis and Lung Disease 23,(8):891-899. Doi: 10.5588/ijtld.18.0609

Dippenaar, A., M. De Vos, F.M. Marx, S.A. Adroub, P.D. van Helden, A. Pain, S.L. Sampson, & R.M. Warren. (2019) Whole genome sequencing provides additional insights into recurrent tuberculosis classified as endogenous reactivation by IS6110 DNA fingerprinting. Infection, Genetics and Evolution 103948. doi: 10.1016/j.meegid.2019.103948

Osman, M., A. Welte, R. Dunbar, R. Brown, G. Hoddinott , A.C. Hesseling, & F.M Marx (2019) Morbidity and mortality up to 5 years post tuberculosis treatment in South Africa: A pilot study. International Journal of Infectious Diseases 85:57-63 doi: org/10.1016/j.ijid.2019.05.024

Marx F. M, Dunbar R, Enarson D. A, Williams B. G, Warren R. M, van der Spuy G. D, van Helden P. D, Beyers N. (2014) The temporal dynamics of relapse and reinfection tuberculosis after successful treatment: a retrospective cohort study. Clinical Infectious Diseases 58(12): doi: 10.1093/cid/ciu186.

DSI-NRF Centre of Excellence in Epidemiological Modelling and Analysis