Larisse Bolton, PhD


Research theme: Other Research Topics

Dr Larisse Bolton joined SACEMA in September 2018. Her research project, under the supervision of Prof Juliet Pulliam, and in collaboration with the South African National Blood Services (SANBS) and Western Province Blood Transfusion Services (WPBTS), seeks to analyse blood product usage, evaluate unmet clinical demand and examine the unmet need, all within the South African context. Larisse holds a BSc in Chemistry and PhD in Applied Mathematics, both obtained from the University of the Free State in Bloemfontein. Her PhD thesis, entitled “Practical approaches to the application of mathematical modelling in oncology: From model investigation to data-driven model construction” was under the supervision of Prof Cang Hui, Prof Thomas Acho and Prof David Stones. Herein, the mathematical modelling of two different cancers were undertaken from two perspectives respectively. The first, model adaptation and the second, model construction. This prior research, as well as her current research, aligns with her overall passion, to use her mathematical skills to aid clinicians and bring about change in pressing health issues.

Recent publications

Bolton, L., T. M. Acho, D. K. Stones, & C. Hui (2020) Describing the evolution of myeloid-derived leucocytes in treated B-lineage paediatric acute lymphoblastic leukaemia with a data-driven granulocyte-monocyte-blast model. Mathematical Medicine and Biology: A Journal of the IMA doi: 10.1093/imammb/dqaa003

DSI-NRF Centre of Excellence in Epidemiological Modelling and Analysis